When peptide amino acid complexes (derived from pancreatin protein extracts) are used as a dietary supplement, nitrogen retention is increased sixteen times compared to crystalline forms of free amino acids
However, a much repeated criticism of studies of MSG taken without food is that the characteristic strong flavor of MSG is difficult to mask, unblinding the subjects to its identity and potentially leading to bias. Even in people who self-identify as MSG sensitive, studies have failed to provide reproducible evidence of an MSG effect. The authors of the largest and most comprehensive of such studies concluded that large doses of MSG given without food may elicit more symptoms than a placebo in individuals who believe that they react adversely to MSG
The study showed a significant increase in body mass index (BMI) and improvement in nutritional status in the L-carnitine group receiving 4 g/day for 12 weeks compared to placebo
There were other effects on reducing some symptoms of type 2 diabetes, including fatigue and insomnia, after 6 months of treatment
Actlabs inserts additional commercial standards in all phases of the analytical procedures, duplicates at multiple stages in the preparation procedures and blanks